- During my early years at Minnesota I conducted an evening enzyme seminar.
[ Conducted During Early Enzyme Evening Minnesota Seminar Years]
- A key issue in developmental biology at that time was the problem of how cells underwent differentiation, with most workers concentrating on explanations in terms of changes in enzyme and gene regulation.
[ Biology Cells Changes Concentrating Developmental Differentiation Enzyme Explanations Gene How Issue Key Most Problem Regulation Terms Time Underwent Workers]
- As has repeatedly been stated, the underlying hypothesis, which in a number of cases has been supported by direct experimental evidence, is that each gene controls the production, function, and specificity of a particular enzyme.
[ Been Cases Controls Direct Each Enzyme Evidence Experimental Function Gene Hypothesis Number Particular Production Repeatedly Specificity Stated Supported Underlying Which]
- These studies resulted eventually in a complete sequence analysis of the complex from several species, and in the atomic resolution structure of the F catalytic domain of the enzyme from bovine mitochondria, giving new insights into how ATP is made in the biological world.
[ Analysis Atomic Biological Complete Complex Domain Enzyme Eventually Giving How Insights Into Made New Resolution Resulted Sequence Several Species Structure Studies These World]